The levels of C-reactive protein, cholinesterase, low-density lipoprotein (LDL), and triglyceride were significantly increased in the GDM group, which are recognized clinical indicators that significantly increase the risk of cardiovascular disease (Figure 4), while the high density lipoprotein (HDL), which is commonly known as “vascular scavenger,” was found to be significantly lower in the GDM pregnancy than the controls in the first trimester of pregnancy. Here, CRP is linked to gestational diabetes.