In addition, overexpression of miR-613 led to diminished DNMT3B protein levels in C666-1R cells, while knockdown of miR-613 brought about an increase in DNMT3B protein levels in C666-1 cells, which underscores that miR-613 targeted DNMT3B. In accordance with our data, elevated DNMT3B expression in NPC tissues has been reported before [37]. The gene discussed is DNMT3B; the disease is nasopharyngeal carcinoma.