To further explore whether miR-613 participated in the regulation of NPC radiosensitivity by inhibiting DNMT3B/TIMP3 and diminishing the activation of the STAT1/FOXO1 pathway, the protein level patterns of STAT1 and FOXO1 in NP-69, C666-1, and C666-1R were detected by Western blot. The gene discussed is DNMT3B; the disease is nasopharyngeal carcinoma.