CIRBP and malignant colon neoplasm: Jang et al. [7] also showed that the expression level of CIRBP was closely related to the prognosis of colon cancer patients, and the 5-year survival rate of patients with high expression of CIRBP was better than that of patients with low expression of CIRBP, suggesting that CIRBP may play a role of tumor suppressor gene in colon cancer.