ITSN1 and inflammatory bowel disease: Studies have shown that lncRNA-ITSN1-2 acts as a competing endogenous RNA for IL-23R via sponging miR-125a, and lncRNA meg3 serves as a competing RNA for IL-10 via sponging miR-98-5p in IBD (Nie and Zhao, 2020; Wang Y et al., 2021).