In addition to SNCA, several EWAS have reported site-specific changes in CpG methylation across a number of genes in individuals with PD, including CYP2E1, MIR886, MAPT, LARS2, and SLC7A11 (Masliah et al., 2013; Rawlik et al., 2016; Chuang et al., 2017; Henderson-Smith et al., 2019; Vallerga et al., 2020; Kaut et al., 2022) (Supplementary Tables S1, S2). The gene discussed is CYP2E1; the disease is Parkinson disease.