By inhibiting phosphorylation of JAK2 and STAT3, which are highly activated in many malignant cells, including glioma cells, miR-33a inhibits the growth, invasion, and EMT of tumor cells (Feng et al., 2016; Chang et al., 2017; Liu et al., 2019a; Liu et al., 2019b). Here, JAK2 is linked to central nervous system cancer.