Additionally, we found that the interferon-related genes (OAS1, MX1, MX2, RSAD2, IFI6, IRF9, IFITM2, IFITM3, GBP1, GBP2, and IFI44L) were upregulated in JAK2V617F+ PMF compared to not only HC but also JAK2V617F+ PV and ET (Figure 7C). Here, IRF9 is linked to acquired polycythemia vera.