Two external datasets [GSE174060 (Baumeister et al., 2021) and GSE120362 (Schubert et al., 2019)] derived from the same GPL platform were utilized and analyzed to verify the inflammation- and immune-related genes overlapping upregulated in different JAK2V617F+ MPN subtypes, with CD34+ HSPC samples of JAK2V617F+ PV (n = 8), JAK2V617F+ ET (n = 2), JAK2V617F+ SMF (n = 3), JAK2V617F+ PMF (n = 10), and HC (n = 6) included. This evidence concerns the gene CD34 and essential thrombocythemia.