Considering the additional three samples from patients with JAK2V617F+ SMF, we finally identified four genes (OAS1, IFITM3, GBP1, and GBP2) with increased expression levels not only in JAK2V617F+ PMF but also in JAK2V617F+ SMF in comparison with HC and PV/ET (Figure 8A). Here, IFITM3 is linked to essential thrombocythemia.