The expression levels of these inflammation- and immune-related genes (ITGAM, FPR1, Fc Gamma Receptor genes, TYROBP, NCF2, ARG1, CCL5, and HP) were significantly higher in both chronic and aggressive fibrotic phases of JAK2V617F+ MPN than those in HC (Figure 5), which confirmed the results described above. The gene discussed is ITGAM; the disease is myeloproliferative disorder.