Considering the additional three samples from patients with JAK2V617F+ SMF, we finally identified four genes (OAS1, IFITM3, GBP1, and GBP2) with increased expression levels not only in JAK2V617F+ PMF but also in JAK2V617F+ SMF in comparison with HC and PV/ET (Figure 8A). This evidence concerns the gene GBP2 and acquired polycythemia vera.