It was found that the levels of several clinical characteristics related to diabetes including age, BMI, HOMA-IR, Insulin, FPG, OGTT-0.5h PG, OGTT-1h PG, OGTT-2h PG, OGTT-3h PG and HbA1c were significantly increased in both PreDM and T2DM groups as compared with those in NC group. This evidence concerns the gene INS and type 2 diabetes mellitus.