Next, we examined the expression profile of NBPF1 in tumors of various pathological stages and cancer subtypes, which indicated that low expression of NBPF1 generally predicted late pathological stage in KIRC and LUAD, larger tumor size in KIRC and LUAD, more lymph node metastases in KIRC, and more distant metastases in LUAD. Here, NBPF1 is linked to cancer.