As shown in Figure 2A, NBPF1 tended to be significantly downregulated in most cancer types, including BRCA, COAD, KICH, KIRC, KIRP, LUSC, PCPG, READ, THCA, and UCEC, suggesting that NBPF1 has an essential anti-cancer role in these cancers, whereas it is overexpressed in CHOL, LIHC, and STAD. The gene discussed is NBPF1; the disease is cancer.