age >18 years; type 1 DM; glycated hemoglobin (HbA1C) 6% to 10%; nephropathy (defined as urinary albumin to creatinine ratio of >2.1 mg/mmol in men and >2.8 mg/mmol in women); and estimated GFR ≥ 80 mL/min. Here, ALB is linked to Nephropathy.