Specifically, the H2AFZ gene (which encodes H2A.Z.1) was downregulated in ACM-cultured T-ALL cells (Figures 2C–E), and high expression levels of this gene are associated with more aggressive solid cancers such as hepatocellular carcinoma (Dong et al., 2021). The gene discussed is H2AZ1; the disease is hepatocellular carcinoma.