RING1 and acute lymphoblastic leukemia: Despite the epigenetic flux observed in ACM-stimulated human T-ALL cells, we did not observe increases in the detection of proteins, which compromise PRC1 (BMI1 and RING1A) or PRC2 (EZH2, EED, and SUZ12), which can monomethylate, dimethylate, and trimethylate H3K7 (Dobrinic et al., 2021).