In addition to metabolic functions, several bioinformatic analyses demonstrated that AGTRAP can be used as a component of prognostic signatures in brain lower grade glioma, tongue squamous cell carcinomas, and melanoma, revealing the potential of prognostic ability of AGTRAP (Loftus et al., 2017; Zeng et al., 2019; Xiong et al., 2020). Here, AGTRAP is linked to central nervous system cancer.