Baratz et al., (2015) studied the effect of TNF-α synthesis inhibitor 3,6′-dithiothalidomide on mice subjected to mild TBI. 3,6′-dithiothalidomide ameliorated the neuronal loss, cognitive impairments and elevations in astrocyte number due in response to mild TBI via preventing mTBI-induced TNF-α elevation Baratz et al., (2015). The gene discussed is TNF; the disease is Cognitive impairment.