REN and kidney disorder: It is reasonable to speculate that the available and well-studied data demonstrating slowing or prevention of kidney disease progression in the general adult population can also be applied to this specific younger population, including the use of renin-angiotensin-aldosterone system blockade agents (RAAS inhibitors), mineralocorticoid receptor antagonists (MRAs), and sodium-glucose co-transporter 2 (SGLT2) inhibitors.