CD274 and neoplasm: Bioinformatics analysis exhibited that LINC00887 level was associated with PD-L1 level, combined with the report that the expression of PD-L1 may affect the functions of CD8+ T cells [23], we detected the protein level of PD-L1 in tumor cells, manifesting that knockdown LINC00887 could inhibit the expression of PD-L1 (Figure 4(a)).