In conclusion, this study preliminarily illustrated the high level of LINC00887 in ccRCC, and it was negatively connected to the abundance of CD8+ T cell immune infiltration; LINC00887 knockdown led to increased cytotoxicity, weakened apoptosis ability, and enhanced chemotactic ability of CD8+ T cells. This evidence concerns the gene CD8A and nonpapillary renal cell carcinoma.