Deletion of ACSL4 in prostate cancer (PCa) cells that express endogenous ACSL4 results in the attenuation of cell capacity to proliferate, migrate, and invade, whereas ectopic production of ACSL4 in ACSL4-negative PCa cells results in an enhancement of the proliferative, migratory, and invasive capacity of cells [20]. The gene discussed is ACSL4; the disease is prostate cancer.