Guaita-Esteruelas et al. (2018) elucidated the role of FABP4 in the tumor microenvironment (TME) to promote carcinogenesis and the development of carcinoma. FABP4 has been proven to promote breast (Li et al., 2019), prostate (Liu and Godbout, 2020), ovarian (Nieman et al., 2011) cancers and other malignant tumors (Figure 2). The gene discussed is FABP4; the disease is carcinoma.