A study by Attal et al. (2021) showed that the expression of FABP4 was upregulated in obesity and chronic alcohol intake, and exogenous recombinant human FABP4 (rhFABP4) stimulated proliferation and migration of HCC cells, all of which indicated the promoting role of FABP4 in HCC. This evidence concerns the gene FABP4 and obesity due to melanocortin 4 receptor deficiency.