AKT1 and neoplasm: Previous studies have suggested that PRR11 plays a vital role in numerous biological processes, such as cell cycle progression; cell proliferation, migration, and invasion; apoptosis; and cell autophagy of tumor cells by regulating cyclin genes (Ji et al., 2013; Zhang et al., 2018), p38 MAPK (Lin et al., 2020), Wnt/β-catenin (Qiao et al., 2019; Zhou et al., 2019), PI3K/AKT/β-catenin (Zhu et al., 2018), and Akt/mTOR autophagy (Zhang et al., 2018) signaling pathways.