Previous cell adhesion molecules study on PSC and primary biliary cirrhosis (PBC) found that the intercellular adhesion molecule-1 (ICAM-1) expression on biliary epithelium in PSC occurs mainly in late stage disease and therefore may be secondary to inflammation, whereas the ICAM-1 expression is less common in PBC [49]. Here, ICAM1 is linked to pancreatic serous cystadenoma.