Conioselinum anthriscoides “Chuanxiong”’ [Apiaceae] and Paeonia lactiflora Pall. [Paeoniaceae] (CA-PL) drug pair could ameliorate cerebral ischemia by inhibiting the inflammatory reaction and apoptosis in MCAO rats on account of down-regulating the expression of caspase-3 and caspase-12 (Gu et al., 2018). This evidence concerns the gene CASP3 and Cerebral ischemia.