INS and type 2 diabetes mellitus: Similarly, the OGTT and ITT AUC of the DMC group were almost 2- to 3-fold higher than the CON group but it was significantly lower in the T2DM animals treated with KHAG-04 (Figures 6C,D) suggesting that KHAG-04 can take part in controlling the glucose homeostasis and insulin sensitivity of the T2DM animals in a positive way.