miR-107 is transcribed from the host gene PANK1, which is broadly expressed in many tissues and has been implicated in cancers (Turco et al., 2020), chemosensitivity (Chen et al., 2021), ischemic stroke (Yang et al., 2014), insulin resistance (Yang et al., 2020), and neuronal differentiation (Croizier et al., 2018). Here, PANK1 is linked to ischemic stroke.