ATX was shown to be upregulated in bronchoalveolar lavage fluid in bleomycin models (Oikonomou et al., 2012) and its inhibition ameliorated LPA levels and pulmonary fibrosis in bleomycin models (Oikonomou et al., 2012; Kato et al., 2016; Desroy et al., 2017). The gene discussed is ENPP2; the disease is pulmonary fibrosis.