CD8A and Alzheimer disease: AD patients presented greater infiltration levels of CD8+ T cells, regulatory T cells (Tregs), gamma delta T cells, Monocytes, M1 macrophages, resting dendritic cells, activated dendritic cells, activated mast cells, eosinophils and neutrophils, which were consensus with the previous studies (Ciaramella et al., 2010; Kwak et al., 2014; Lehrer and Rheinstein, 2016; Stock et al., 2018; Kapellos et al., 2019; Salminen et al., 2020).