TGFB1 and chronic kidney disease: Our previous studies showed that poricoic acid A could block AKI-to-CKD progression and renal fibrosis by modulating the Wnt/β-catenin pathway in renal ischaemia‒reperfusion injury and hypoxia/reoxygenation- or TGF-β1-induced HK-2 cells (Chen et al., 2019d).