In addition, Shin et al. (2021) reported that this allele was detected in 66% of Africans, 53% of Americans, 54% of European, but only in 31% of South Asians, whereas that of ARMS2 rs3750846 SNP was detected in 26% of Africans, 25% of Americans, 19% of Europeans, suggesting  the existence of genetic differences among racial and ethnic groups, affecting consequently AMD prevalence, that was higher in East Asians than in Europeans due to genetic predisposition in East Asians [21]. The gene discussed is ARMS2; the disease is age-related macular degeneration.