In 2012, the same group presented similar results on SSc-lung fibroblasts, which showed overexpression of Betaglycan and Endoglin; when a transient transfection further increased the levels of these accessory receptors, they inferred an altered cellular response to TGFβ, by quantifying the expression of fibrogenic genes (56). This evidence concerns the gene TGFB1 and systemic sclerosis.