GSEA results showed that REACTOME_SCAVENGING_OF_HEME_FROM_PLASMA (A), REACTOME_FCGR_ACTIVATION (B), REACTOME_CD22_MEDIATED_BCR_REGULATION (C), REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS (D), REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION (E), and REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS (F) were enriched primarily in FECH-associated ccRCC. Here, FECH is linked to nonpapillary renal cell carcinoma.