The correlation between the nectin family and immune cell infiltration in liver cancer tissues was analyzed by TIMER, and the results showed that nectin-1 positively correlated with B-cell, CD4+ T-cell, macrophage, neutrophil, and DC infiltration, while nectin-2 was positively correlated with B-cell, CD4+ T-cell, neutrophil, and DC infiltration; nectin-3 did not correlate with any type of immune cell infiltration; and nectin-4 positively correlated with B cell, CD4+ T cell, macrophage, neutrophil, and DC infiltration (Figures 7A, B). The gene discussed is CD4; the disease is liver cancer.