Many studies have concluded that the risk factors of IVR after RNU include tumor stage, multifocality, preoperative ureteroscopic biopsy, male, previous history of bladder cancer, smoking, chronic kidney disease, tumor location, transurethral bladder cuff resection, positive resection margin, and surgical approach (4, 14–16), At the same time, there was also an article that has shown the independent role of biochemical parameters such as triglycerides to HDL cholesterol ratio and pseudocholinesterase levels in predicting the presence of bladder cancer (17). This evidence concerns the gene BCHE and urinary bladder carcinoma.