On the other hand, the overall inhibitory effects of cell growth (Figure 5A), colony formation (Figure 5B), suppression of cell migration (Figure 5C, D), and increase of cell apoptosis (Figure 5E) warranted that the effects of ZNF280A knockdown on CRC development could be attenuated or reversed by the overexpression of RPS14, highlighting the role of ZNF280A/RPS14 axis in CRC. The gene discussed is RPS14; the disease is colorectal carcinoma.