(23) determined that HuR could bind to lncRNA AGAP2-AS1 to stabilize AGAP2-AS1 expression and the AGAP2-AS1-HuR complex upregulates H3K27ac level in MTA1 promoter region to improve MTA1 promoter activity and expression, thereby inducing the resistance breast cancer cells to apoptosis (Figure 5). The gene discussed is MTA1; the disease is breast cancer.