(2010) showed that H630 colon cancer cells resistant to trifluorothymidine (TFT), a fluorinated thymidine analog that is part of TAS-102 chemotherapy and shares the anabolic pathway of TS inhibition with 5-FU, underexpress OGT, Solute Carrier family 29A (SLC29A), and TK (77). This evidence concerns the gene OGT and malignant colon neoplasm.