The expressions of NAV1, SIPA1L2, FMN2, MMP28, SETBP1, EIF4E3, MICU3, and RUNX1T1 have shown to be decreased in CRC samples and reduced expression levels of SIPA1L2, MMP28, and EIF4E3 are associated with lower overall survival rates in CRC patients. This evidence concerns the gene EIF4E3 and colorectal carcinoma.