To date, the etiology of IMT remains inconclusive, although recent studies have shown that IMT is associated with anaplastic lymphoma kinase (ALK) gene rearrangements, as well as overexpression of ALK protein, and the disease also involves fusion of genes such as ROS1, NTRK3, and RET (7–10). The gene discussed is ROS1; the disease is inflammatory myofibroblastic tumor.