ALT/WDL/DDL accounts for 50-60% of all liposarcomas and is characterized by the amplification of 12q13-15, including several oncogenes, such as MDM2, CDK4, FRS2, HMGA2, and CPM. The term “ALT” is used for tumors located in the site where surgical excision can be carried out and is curative, and the term “WDL” is used for lesions arising in sites such as the retroperitoneum, spermatic cord, and mediastinum, where tumors have a greater possibility for progression (1, 2). The gene discussed is GPT; the disease is liposarcoma.