CD274 and non-small cell lung carcinoma: When the PD-L1 inhibitor durvalumab was given to NSCLC patients after concurrent chemoradiotherapy, investigators saw an increased OS rate (66.3% in the durvalumab group vs. 55.6% in the control group), increased PFS (17.2 months for durvalumab group vs. 5.6 months in the control group), and increased median time to death or distant metastasis (28.3 months in the durvalumab group vs. 16.2 months in the control group) (13).