found that oxygen glucose deprivation/restoration conditions resulted in a significant increase in the LC-II/LC-1 ratio and a decrease in p62 expression in alveolar macrophages accompanied by the upregulation of autophagy, while pretreatment with bone marrow mesenchymal stem cells (BMSCs) reduced macrophage autophagy and attenuated the ischemia/reperfusion-induced inflammatory response in ALI mice (153). Here, SQSTM1 is linked to acute respiratory distress syndrome.