TLR4 and autoimmune hepatitis: Moreover, a compound of 15 probiotics has been reported to decrease hepatic inflammation, serum transaminase levels, Th1 and Th17 cells, and increase the number of regulatory T cells in a murine model of AIH, while protecting intestinal barrier integrity, blocking lipopolysaccharide (LPS) translocation, inhibiting the toll-like receptor 4/nuclear factor κB (TLR4/NF-κB) pathway activation and the production of inflammatory cytokines in both liver and ileum (69).