As a result of the activation of CD4 T cells, eosinophils, gamma delta T cells, regulatory T cells, mast cells, active dendritic cells, neutrophils, type 2 T helper cells, CD56 dim natural killer cells, immature dendritic cells, and immature B cells, the immunological activation of the breast cancer subtypes was also substantial. The gene discussed is NCAM1; the disease is breast cancer.