The result showed that in univariable logistic regression, PHI-based biomarkers and serum cytokines TRAIL, IL-10 were all associated with AG PCa, while multivariable analysis demonstrated that tPSA, fPSA, PHI, IL-10, and TRAIL were the 5 independent risk factors but age and p2PSA were excluded (Table 2). The gene discussed is IL10; the disease is posterior cortical atrophy.