Analysis of DEGs obtained from the GSE41861 and GSE23552 datasets showed that CST1 was the only gene co-expressed in the nasal mucosa of asthma and ACRSwNP patients; that is, compared with normal controls, CST1 was highly expressed not only in the inflamed mucosa and nasal polyps of ACRSwNP patients, but also in the nasal mucosa of asthmatic patients. The gene discussed is CST1; the disease is asthma.