HERC3 and autoimmune disease: We also found that IFNβ-unique peaks contained Trim26, Herc3, and Asb13, while sgScd2-unique peaks contained F830016B08Rik, Gbp2b, Oas2. In particular, Trim26, Herc3, Gbp2b and Oas2 are known to be related to the progression of autoimmune disease (Figures 4H, I and Supplementary Figures 4A–D).