Few genes and pathways associated with colon cancer are nuclear factor kappa B (NF-κB), mitogen-activated protein kinase (MAPK) pathways, leptin, cyclin D, matrix metalloproteinases (MMPs), signal transducer and activator of transcription-3 (STAT-3) genes, chromosomal instability pathway (CIN), and DNA mismatch repair system (MMR) [4]. Here, STAT3 is linked to malignant colon neoplasm.