Among all the associations, HO1 expression was significantly correlated with CTLA4, CD48, CD200R1 (CD200R), HAVCR2 (CD366), PDCD1LG2 (CD273), TNFRSF8 (CD30), VSIR (VISTA), CD40, CD86 and TNFRSF9 (CD137) in AML (Fig. 2A). Here, CD48 is linked to acute myeloid leukemia.