To figure out the biological relevance of miR-877-5p in CML and whether BCR-ABL is controlled by miR-877-5p, the expression level in BMMCs from CML patients was determined (Fig. 5A), then inhibitor or mimics was utilized to knock down or overexpress miR-877-5p, respectively. Here, ABL1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.