Recent studies have shown that abnormally expressed lncRNA TCF7 can predict poor OS in MM patients,23, 24 but not the abnormally expressed lncRNA ANRIL,18 and the aberrant expression of lncRNA MALAT1 was not associated with clinical outcomes in MM patients,25 indicating the ambiguous prognostic significance of lncRNAs in MM. This evidence concerns the gene MALAT1 and Miyoshi myopathy.