CEACAM8 and neoplasm: Our previous report clarified that 6G5j can bind to CEACAM1, CEACAM3, CEACAM5 (conventional CEA), CEACAM6, and CEACAM8.17 The ability to bind to multiple CEACAMs may improve the binding capacity of the antibody and enhance the visualization of tumor margins that are otherwise invisible compared with CEA alone.