A recent murine model of diabetes (Yang et al. 2019) suggested that variation to blood glucose levels weakens the myelin sheath and nerve fibres and induces inflammation, particularly increased pro-inflammatory cytokines such as tumour necrosis factor alpha (TNF-α), interleukin-6 (IL-6) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-KB). This evidence concerns the gene IL6 and diabetes mellitus.