SIL promotes the expression of SIRT1, FoxO1, CAT, GPX1 and SOD2 of hyperglycemia Intervention of MC3T3-E1 by reducing intracellular ROS levels and restoring the activity and function of MC3T3-E1, similar to those from some researches [44, 45]. This evidence concerns the gene SIRT1 and Hyperglycemia.